Claudio Festuccia Selected Research

PBI-05204

1/2022	The botanical drug PBI-05204, a supercritical CO2 extract of Nerium oleander, sensitizes alveolar and embryonal rhabdomyosarcoma to radiotherapy in vitro and in vivo.
1/2022	The Botanical Drug PBI-05204, a Supercritical CO2 Extract of Nerium Oleander, Is Synergistic With Radiotherapy in Models of Human Glioblastoma.
1/2020	The Botanical Drug PBI-05204, a Supercritical CO2 Extract of Nerium Oleander, Inhibits Growth of Human Glioblastoma, Reduces Akt/mTOR Activities, and Modulates GSC Cell-Renewal Properties.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Claudio Festuccia Research Topics

Disease

67	Neoplasms (Cancer) 10/2023 - 01/2002
59	Prostatic Neoplasms (Prostate Cancer) 10/2023 - 01/2002
22	Glioblastoma (Glioblastoma Multiforme) 01/2022 - 12/2005
9	Carcinoma (Carcinomatosis) 12/2014 - 01/2002
8	Rhabdomyosarcoma 01/2022 - 01/2011
8	Neoplasm Metastasis (Metastasis) 12/2019 - 05/2004
7	Glioma (Gliomas) 01/2022 - 12/2005
3	Sarcoma (Soft Tissue Sarcoma) 01/2022 - 05/2015
3	Brain Neoplasms (Brain Tumor) 01/2022 - 05/2018
3	Embryonal Rhabdomyosarcoma 01/2022 - 01/2011
3	Carcinogenesis 05/2017 - 12/2005
3	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 03/2013 - 04/2004
2	Osteolysis 12/2019 - 09/2015
1	Adenocarcinoma 10/2023
1	Mitochondrial Diseases (Mitochondrial Disease) 05/2022
1	Wounds and Injuries (Trauma) 01/2020

Drug/Important Bio-Agent (IBA)

17	AndrogensIBA 04/2018 - 03/2003
10	Hormones (Hormone)IBA 12/2017 - 06/2009
10	bicalutamide (Casodex)FDA LinkGeneric 12/2011 - 09/2002
9	Androgen Receptors (Androgen Receptor)IBA 12/2017 - 01/2003
9	DNA (Deoxyribonucleic Acid)IBA 01/2017 - 11/2010
9	ErbB Receptors (EGF Receptor)IBA 10/2011 - 03/2003
6	Phosphotransferases (Kinase)IBA 01/2020 - 07/2004
6	Cyclin D1IBA 12/2017 - 06/2009
6	Tyrosine Kinase InhibitorsIBA 10/2009 - 03/2003
5	EphrinsIBA 10/2023 - 10/2017
5	Docetaxel (Taxotere)FDA Link 12/2019 - 06/2009
5	Gefitinib (Iressa)FDA Link 11/2007 - 03/2003
4	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2022 - 10/2013
4	Mechanistic Target of Rapamycin Complex 1IBA 01/2022 - 08/2011
4	Therapeutic UsesIBA 11/2021 - 01/2015
4	Histone Deacetylase InhibitorsIBA 10/2021 - 03/2012
4	Temozolomide (Temodar)FDA LinkGeneric 01/2020 - 01/2017
4	Proteins (Proteins, Gene)FDA Link 10/2019 - 01/2002
4	Azacitidine (5 Azacytidine)FDA Link 07/2016 - 05/2008
4	selinexorIBA 01/2016 - 10/2014
4	Epidermal Growth Factor (EGF)IBA 11/2006 - 05/2004
3	PBI-05204IBA 01/2022 - 01/2020
3	thiamine triphosphorate (TTP)IBA 01/2020 - 06/2014
3	trans-sodium crocetinate (crocetin)IBA 01/2020 - 01/2014
3	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 01/2020 - 01/2014
3	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2020 - 05/2017
3	Mechanistic Target of Rapamycin Complex 2IBA 10/2019 - 08/2011
3	belinostatIBA 10/2019 - 03/2012
3	crocinIBA 01/2019 - 01/2013
3	Histone Deacetylases (Histone Deacetylase)IBA 01/2019 - 01/2017
3	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 09/2018 - 01/2011
3	PyrimidinesIBA 01/2017 - 11/2006
3	SurvivinIBA 01/2016 - 06/2014
3	LigandsIBA 01/2014 - 12/2005
3	MethyltransferasesIBA 03/2013 - 11/2010
3	Androgen Antagonists (Antiandrogens)IBA 10/2009 - 09/2002
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 04/2005 - 10/2002
2	Eph Family Receptors (Eph Receptors)IBA 10/2023 - 01/2020
2	Peptides (Polypeptides)IBA 01/2022 - 10/2002
2	oleandrinIBA 01/2022 - 01/2022
2	EphA1 Receptor (Eph Receptor)IBA 01/2020 - 05/2018
2	Erythropoietin FDA Link 01/2020 - 10/2017
2	Protein Kinases (Protein Kinase)IBA 01/2020 - 01/2011
2	Collagen Type I (Type I Collagen)IBA 12/2019 - 09/2015
2	AntioxidantsIBA 04/2019 - 01/2019
2	givinostat hydrochlorideIBA 01/2019 - 01/2019
2	Carotenoids (Carotene)IBA 01/2019 - 01/2014
2	givinostatIBA 01/2019 - 01/2019
2	U 0126 (UO 126)IBA 09/2018 - 01/2011
2	Testosterone (Sustanon)FDA Link 04/2018 - 12/2017
2	Antineoplastic Agents (Antineoplastics)IBA 01/2017 - 09/2002
2	Nerve Growth Factor (NGF)IBA 07/2016 - 01/2007
2	Exportin 1 ProteinIBA 12/2015 - 12/2014
2	KPT-251IBA 12/2015 - 10/2014
2	palomid 529IBA 06/2014 - 08/2011
2	lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA 06/2014 - 01/2011
2	Erlotinib Hydrochloride (CP 358,774)FDA Link 10/2011 - 10/2009
2	Cisplatin (Platino)FDA LinkGeneric 08/2011 - 06/2009
2	Phosphoric Monoester Hydrolases (Phosphatases)IBA 11/2009 - 08/2007
2	TensinsIBA 11/2009 - 08/2007
2	Finasteride (Propecia)FDA LinkGeneric 07/2008 - 04/2005
2	lestaurtinibIBA 09/2007 - 01/2007
2	OsteopontinIBA 05/2004 - 01/2002
1	prochlorazIBA 05/2022
1	Glutathione (Reduced Glutathione)IBA 05/2022
1	Superoxide DismutaseIBA 05/2022
1	Ketoconazole (Nizoral)FDA LinkGeneric 05/2022
1	AzolesIBA 05/2022
1	Miconazole (Monistat)FDA LinkGeneric 05/2022
1	Cell-Penetrating PeptidesIBA 01/2022
1	Proliferating Cell Nuclear Antigen (PCNA)IBA 01/2022
1	Cardiac GlycosidesIBA 01/2022
1	ABTL0812IBA 01/2022
1	sulforaphaneIBA 10/2021
1	entinostat (MS 275)IBA 10/2021
1	Cyclin AIBA 01/2021
1	romidepsin (FK228)FDA Link 01/2021
1	CytokinesIBA 08/2020

Therapy/Procedure

25	Therapeutics 10/2023 - 07/2004
19	Radiotherapy 01/2022 - 01/2010
10	Drug Therapy (Chemotherapy) 01/2020 - 12/2005
9	Castration 12/2019 - 10/2009
2	Oral Administration 12/2015 - 08/2010
2	Prostatectomy (Retropubic Prostatectomy) 09/2007 - 09/2007